Since things have been going so well lately, there's nothing exciting to report and thus the lack of recent posts.
I got up this morning and checked my Google homepage which I have set up to show me the latest feeds in Multiple Sclerosis news. Much to my delight there was an article about Finglimod (FTY-720) in today's news!
It seems that clinical studies have now shown that not only does Fingolimod slow the progression of MS but also aids in repair of previous damage to the nerves.
Full story is found here:
http://www.engelpub.com/News/Index.cfm?articleid=483828
EAST HANOVER, N.J., Oct. 12, 2007- New preclinical data presented at European Committee for Treatment and Research of Multiple Sclerosis (ECTRIMS) in Prague suggests that FTY720 (fingolimod) directly reduces neurodegeneration and enhances repair of the central nervous system (CNS) damage caused by multiple sclerosis (MS) by interacting with sphingosine-1-phosphate receptors (S1P-R) expressed on brain cells. This mechanism of action may be in addition to the established anti-inflammatory role of FTY720 that is mediated by the reduction of inflammatory immune cells, called lymphocytes, from reaching the brain.
To me that means a world of hope. Not only does it mean no more shots, and a strong ally in the form of a drug to help slow progression, but now it may also mean reversal of damage. How wonderful! There is some hope that maybe my legs won't feel like they're on fire for the rest of my life.
I sometimes complain and often fret over having MS and what it's done to me, but when I stop and think about it, I've really had it made. I could be so much worse off after nearly 9 years, but to look at me today you'd never know there was anything wrong.... which is why I sometimes hesitate to use my blue parking permit. I hate the stares of people trying to shame me when they see me get out of the truck and walk -- as if I'm as normal as the next person -- into the store. What they don't bother to do is follow me for 100 feet and see that I'm no longer looking so "normal" any more, but I'm now dragging my feet and leaning on the shopping cart.
But that's another story. My point is that I have a lot to be thankful for. First and foremost I'm glad that if I had to have this terrible disease, at least I got diagnosed during a time of hope, when so much is being learned and so many breakthroughs are being made in medicine.
I'm especially thankful to be able to say I'm doing my part in helping to work toward a cure. I know fingolimod isn't a cure, but it's a step in the right direction. To toss the needles of MS therapy and reach for the little pill is, well, nothing short of a miracle and the next best thing to finding a cure.
So to all you researchers out there who may wonder on occasion if you chose the right line of work, I want to say YES! YOU DID! and please know that there's a world of MS sufferers out there who thank you as much as I do.
